Reading through the Bible
I will be using Jerry Seinfeld's "don't break the chain" productivity plan and the accompanying web app to keep me on task. I would also suggest watching this crash course in How to Study the Bible by David Platt. A PDF is also available if you don't have time to listen; although the 6 hour investment is totally worth it.
Skip a day or week?
Don't frickin' worry about it. Don't try to catch up. Just read the suggested passages one day at a time.